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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3377bf84c017c9f51bada6e173d13415e9214ecd5eeff5230576a4380759e45a' 
  AND token = '1AnMoABTJ6v/Re2MEgepeA0JyJkmSTKmXHzq8F5P2vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}