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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4781dcd47f6828d7a1c9f73b5eeb9d9333e5c34572b3ddb0fa4336414f0cdb2' 
  AND token = 'tIV0yoeXHFlkeLDTiFvPQpHMAZ8wCPGk2JLF9vTaNIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}