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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e43ad741b1c7484ba136f6162c9c21045fc2670cb85e6c234b5189a231abdd0' 
  AND token = '9EHShC/UOM3p0aF0gW4SpraJhw3AIh37cLZtKpzwbRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}