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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58f9b7d8e6cc3d155af7187ece89b651b2a6d9b8ee781f81dfeeac584c010350' 
  AND token = '/ytGsid87KgBijPIwxAXppvUHue1fXe5598eoJiBams=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}