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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acebe8508b1b5b8eb8bb1947404a30180716742b769feb82672244fa348bd2a9' 
  AND token = 'B2zyG2dLLG6SkXj+/tdmPkhVPn6nUk61GfGzJHLQ3so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}