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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3bf3cd53e27b49d1889ba8ae01e775168994be3781c6c57e48dd4017cb7e8d' 
  AND token = '3Sot2E7Qh5Lu/a+OSzN/vr0DxX4slFbBPeox66M7xVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}