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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2194d0ee72f456fee664e6eaab9b8e77c26fd1690ee8487b728872639c434db' 
  AND token = '+jg66InVT6AiUulv41sDYADS9WFHo+uOfUUUKlbGtd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}