SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fbb10f3c5a0ec4727651a9f94beaa013bd187cf9cb990f3b523945e47f9e143' 
  AND token = 'noDXvMT2xterX9EGMSsoK4oAvMBBo/khCMkjsEJRCQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}