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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e0924771beaaea0469634467c939d7c852a5feaa4fdf12cb0076675f7a1997' 
  AND token = '9UcM/Ll/O7hqiEMcmzIqWjnIdlVf31HW7pooNmD52b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}