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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9335dad786df13bc12e149476681f28cccfee00e3f69a61f409ea502e9d71e1e' 
  AND token = '+NYQaB7HlxOkdhZwvmyfeDMTzYm3vtQ/N+6f+x3EuEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}