SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278e121532fa8d3e372066cd247223050f3e91720311ea3d65121b92f01be837' 
  AND token = 'cq9yDwITqenVzkR7wFkCQYzmh/7rji0bVK1gsyUub3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}