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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f809501cc4c666efd678f1d0c86d34b22a3681aaeb0f963ad6be54e6d78562' 
  AND token = 'lDdc81iqYevbFaG1KVrl5cGU13M/8yVY1T/4i3JQCME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}