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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5df4cdd228351ddd138db535dd515e6305f42c0f0d2f895e76e0c806ef70f6' 
  AND token = 'ewNEjjCpn0+Ka5mWuY2aFY5T+X4sOHfPjmB+TtJAoIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}