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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455a0ec68b43d98fe695544315d12b7cca6c8f6716528fd3b5b23e13e0383e58' 
  AND token = 'Q/oGtIyIgQDfffkgeBTyBHOB1h5qdpx5x+kz2pV6wEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}