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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbe87a7c6fd608ae164963993028333dd50859d6310920119f423af937e513e5' 
  AND token = 'vtN9/yJ0x30KsQ6fcTOUfWy6VT/5jDiFNXr73aYhZj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}