SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a2c4397a5a25b76fb4b0f365839d1e77835eb554f42c35a0ec64e4e3992d2a' 
  AND token = 'uOP8Bi2MdZ7cAd5EXq33EgGyllOuPkstimC1pqD9vrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}