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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a581cd87aae436cd8ccf4a0e314e8c00ae9075054bd755cc484477f77102a5e' 
  AND token = 'naAFiYWvCqaGUIFV9dXeyloz+daAwDpReFqsnMsxUjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}