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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8167c091a31ccdf9a2c251aa443a4650500e335e7a81f9b0f8ada5532686b8ff' 
  AND token = 'pLrLbLsXiPy2BkrJVvcIn0X1gz4oNG6jj7EpU6IEKuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}