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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561db81d6949ecb1d1d3f498ae4621f3be306ff015d1282a40fbc23466a71661' 
  AND token = '9MxyO5yg9Xueb5I0v3GmJ4KCLvUGeOL4mCfeZulH/pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}