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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e251f9f05f20a252494c0970ee3a705a8bdfa0b926a3d989ae5c0bb2c6fed677' 
  AND token = '2dYhVNXczBSmj/XMriKsEuK4Kdyk0Sh8ZBM5iM435k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}