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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52176ea9ce9a0e0a031d7afa373935e4d6a90d0df4475e1a9c9a7c6c52edba0a' 
  AND token = '7jRB5M+MbUKFvTpRWz97GXI4/U750vhtDbrpKIv2sx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}