SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c368736180febb1df38ac3404f05090ea8c023bbc2f08514d49ab31c0cbbe6' 
  AND token = 'ZCoOqaFXAuNqhB7TwbIEOSYDr/XCi+sSUIY6cBrL6rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}