SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd26c9b749f9c9a9704aaba1895d10305906c16d0c2715e3ab051c7a4154a7f' 
  AND token = 'LJW4av2OpiK1LD9eGh75UN99u5e9aj7cQmwCJ1UjZoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}