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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b43b42b5c6aced796886105853f48619a1c1f7d2718d032d502d30cb17a5e1a' 
  AND token = 'Uqt+Kg9F3nNS6cWhvq2cLfHQXohcBMK1Emk+i8KE6Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}