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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774f006a22fc8500566b89d0c09851d6d054fcb77041f3ac5c4d4cebda26136c' 
  AND token = 'TOGI1hvaOrMccCpGhHHou0FmJBbgX34sjwJ+nxB3bdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}