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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e64c88138de897c4f45584be4d5c2da9a5c31db7a2ae6a287825a6d64f79980' 
  AND token = '+ueRlEIg2YFsElBgtx9fA2qzErjJsywSmHdV57wxTgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}