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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13e2e1144f4a11ff2d9f5aeb4c2cb1f575ea13edbc3cee04c66a779f590fbfd9' 
  AND token = 'gL38+5mg1ZF/8uR3mUYmbVgyPSIPuNYJmtkxOszduO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}