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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '134a8fb5ce6c539b85ca6b950c2f8fba110e9867ca3ea6f814372b5c177f42e2' 
  AND token = 'HuxOfrNTOwg/RKKpxWaRLZ/p/fG3QMKDhL5cQjfdct0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}