SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4353279ab51e51b5667a15a9486930934fe0e55dad8c2f49327a3b9c144d074' 
  AND token = 'iPktClSy6DoDonSLEOAJ7y0Hgs0GWIX0cQzHvy2ckG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}