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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a9f0395839d37096465290eaf41a78371795a26e8d260e081d1d70c290054f9' 
  AND token = 'MtaJhqSB1+VK4cNpIEAfpNPT7YQn73YR4uHiC1Wd2hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}