SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2369228240abc19c365b7bf6b1e5de09d9d50a8403ac3f48e98ee966266ccc3f' 
  AND token = 'Hr8/S3El7PkdTGp8Qou2SSK73W0FVgiG2HTSJiayiAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}