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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd646b026c4b79c91b65886fcb904f257e6d80430b8331d8151b8236b390ba810' 
  AND token = '0aXJCkqT6m4B0AKggQ6HR0PRaPOc7+NUC3JD9ifHBlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}