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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb3d7fa1124a06e71ed5dd33273d8d0b683f68644ec333ac78dc12eae49025d' 
  AND token = 'qJcAsN7Ln433ZVQROdqLTPNmW7Xl/n/CQpepi1UW4rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}