SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71ce81caa92b3232ee1e849a9fbae6c6a708d7ca06ed78a408508d6658b4c2e5' 
  AND token = 'CMWdRXxelUUCPI3R3IVVDaHCTWlr57vo1ao9o6l89ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}