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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ee54964d2d29585464a7c51a1b70ab9d06622369d3b9ec56d06e9ac87ade19' 
  AND token = 'n8y0MyS6HwDpifPQdmsO8U3c42//LoSG5Jkb5fQrZsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}