SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499cfbffada1f151761ef2667ab313d00c8f34f50705e84c9f602697d619329f' 
  AND token = '132d9I8Z+jarFSeRHZelgaqBsUySBvVUo9S50A+K/dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}