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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74453b5af09c14a13ca5776a701575e3b0fcb53a0fdafe2b102653ad0c0cd7aa' 
  AND token = 'G+y32wA9Pg2EnG5xsLdGsAtOU5NV/4xVhbk39q5uOWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}