SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41b31d7dec3e61263b1c007445bce262cb07b7a05fdfcf38fc41f3a15996e73' 
  AND token = 'Cfej3ul77EAaTLZn2Lcj0742ZqHHgQevwbSSfSkkbhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}