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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e78cb9870351be1272b96f4b8f0d18626e77093ad3aed1679946c87d1df340' 
  AND token = 'bQ88FoBmrf8amnUvEU1+c9U98Cw0cPvJ0gQ7PYRhBuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}