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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b826980be50582c9aea8f6bf2614443d07fef2cf8ba449a4b23ec8fd9ce784' 
  AND token = 'Qx7km6/qDYQ9VvF9jWUdKzUjMrPeobzed5BPWLFLe/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}