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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d419077ab7527750e4c0d67c814add8af06476b3902bf198a8ce333a417f67b' 
  AND token = 'G8o1Cua82GlxMsIDZ8kZZ8tee9Pmf4/2D0gztYv/TKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}