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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6573b85cca5c2b7f8ae39f4ef41b7b5d5e7aedad5de09add2b59d445f922ee5f' 
  AND token = '2VLHLE6Hi2B9rnEzFu9Id9ieOAeu77sOtbHAw/K3Xvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}