SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55488f04ace948599cb09ab9d25f2cbfdfdbb6b7fc744be16e579075cba49e25' 
  AND token = '7ZuKQ5IWdxMz4KoRkV9dnE3JEVHK1UZS5yS1JB8Qs5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}