SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbc32e7868c6dcb328969331ea2e82d3a0e63d8261996259394da136d0390f6' 
  AND token = '5OHfKWm8d1LePAvzDnBoYsfK0j7RJTUuV46HQamCqLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}