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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7721a8bb44db4f84b8a7dc2d1dcd72283f28bf1aff5144b1d83f910f517f0970' 
  AND token = 'SiT9MqNzXUEvGbaUsr7UmP8FNc6IDjq8LVPNcZ9xH1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}