SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22559a1a99ea7fd6c54c8cdd86bfb902f46549c95667d8c5c2a461ddcdcf7640' 
  AND token = '9YKG0zpLyMmQ9OIZAANFpYB1MzEfOnE+WQMrvQwiBMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}