SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6496a864c378a822c9fcc08f7dc758b001641fecd21f010b01457a4628b0bf5' 
  AND token = 'jAq2MakRfzlS+2yh8yeBnsDAY+5z5Vz8bQ0zoV+/N4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}