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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e53d745a888edc8ce272b7709010690ac3e0e5f427d1bd88af712e15e5c39c2' 
  AND token = 'm+6wHEjD7fhyC1nD7zwj3DOxOFOxkaADxrG39TVWedE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}