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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d81e22626305ff42fd508517589416fb985d7d0d2a46fb06e75131fb8fd7b94' 
  AND token = 'BqygDmips4UBkPq8cZEMZJURP+bF0hLpugbefcHMhD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}