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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e106b290f5906eaf3691d30393e5169a9e4a8bd4e479d731eead3b24de1949' 
  AND token = 'FB33H6/aeBulJVnXYERLUw9byicFHGm2o8hk5h8HbfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}